The Monastery of Panagia tis Spilias (Panagia of the Cave) is located at Ano Argithea (Agrafa Mountains) in the Karditsa perfecture, near Koympoyriana village. The Monastery was built at 880 meters high at the edge of a high rock.
There are two churches in the Monastery. The first was built in 1604 by Parthenios and Athanasios, brothers from the village of Stefaniada. They built the first church after the miraculous finding of the Panagia Odigitria icon.
This Monastery was a very important place during the Greek War of Independence againt the Ottoman Empire in the 1820's, and the famous Greek warrior Georgios Karaiskakis used this place for war meetings between the local captains.
It celebrates its feast on the Friday of Renewal Week in honor of the Life-Giving Spring.
