“A tomb now suffices him for whom the whole world was not sufficient.”
-- Unknown quote about Alexander the Great

It is only in light of these things that the great ascetic feats of the Desert Fathers make sense, as well as that of contemporary monks and ascetics (and even the ascetic practices of Christians living in the world).
Many incidents from the life of St. Sisoes can be found in the Sayings of the Desert Fathers (Apophthegmata ton Pateron). This Saint, great and renowned among the ascetics of Egypt, lived in the fourth century in Scete of Nitria. After the death of Saint Anthony the Great, he left Scete to live in Saint Anthony's cave which was abandoned; he said of this: "Thus in the cave of a lion, a fox makes his dwelling." St. Nikolai Velimirovich writes of him in his Prologue: "Imposing difficult labors on himself, he humbled himself so much that he became meek and guileless as a lamb. For this God endowed Sisoes with abundant grace so that he was able to heal the sick, drive out unclean spirits and resurrect the dead. Sisoes lived a life of austere mortification in the wilderness for sixty years and was a source of living wisdom for all monks and laymen who came to him for counsel and advice."

Here are some of the wise sayings and illustrious deeds of this great Father of the desert:
- St. Sisoes taught the monks: "Regardless in what way temptation comes to man, a man should give himself to the will of God and to recognize that temptation occurred because of his sins. If something good happens, it should be said that it happened according to God's Providence."
- One monk asked Sisoes: "How can I please God and be saved?" The Saint answered: "If you wish to please God, withdraw from the world, separate yourself from the earth, put aside creation, draw near to the Creator, unite yourself to God with prayers and tears and then you will find rest in this time and in the future."
- Another monk asked Sisoes: "How can I attain humility?" The Saint replied: "When a person learns to recognize every man as being better than himself, with that he attains humility."
- Ammon complained to Sisoes that he could not memorize the wise sayings that he read in order to repeat them in conversation with men. The Saint replied to him: "That is not necessary. It is necessary to attain purity of mind and speak from that purity placing your hope in God."
- Another brother asked Abba Sisoes, "I have fallen, Abba; what shall I do?" The elder said to him, "Get up again." The brother said, "I have gotten up again, but again have I fallen." The elder said, "Get up again and again." So the brother asked, "How many times?" The elder replied, "Until you are taken up either in virtue or in sin. For a man presents himself to judgment in that state in which he is found."
- One day a man came wanting to be a monk and he had a son. Sisoes commanded him to throw the son into the river, which he was only just stopped from doing by the brothers who brought the Elder's counter-command. He went on to become a proficient monk having learned the value of obedience as a means to attaining humility.
- Another man from the world came to Sisoes with his son, who died on the way. The father prostrated himself before the Abba, leaving the boy's corpse there. Thinking the child had merely failed to get up again after the prostration, Sisoes commanded him to arise; which he did, and went out, whole. Sisoes was distressed for he did not intend to raise the dead; he charged everybody to keep silent concerning this matter for as long as he lived.
- A brother who had been wronged by another brother came to see Abba Sisoes. He said to him, "My brother has hurt me and I want to avenge myself." The old man begged him, saying, "No, my child, leave vengeance to God." The brother said, "I shall not rest until I have avenged myself." The Elder said, "Brother, let us pray." Then he stood up and said, "God, we no longer need You to care for us, since we do justice for ourselves." When he heard these words, the brother prostrated himself before the Elder's feet and said, "I will no longer seek justice from my brother. Forgive me, Abba."

Sisoes died in extreme old age in the year 429 A.D. It is the details of his death that he is most famous for. In light of Plato's Phaedo, St. Sisoes died as a true philosopher and lover of wisdom after having purified himself to become an illumined temple of the Holy Spirit.
"They would say of the venerable Sisoes that, when he was at the end of his long life of labors, as the fathers were gathered about him, his face began to shine as the sun, and he said, 'Behold, Abba Anthony is come;' then, 'Behold, the choir of the Prophets is come;' his face shone yet more bright, and he said, 'Behold, the choir of the Apostles is come.' The light of his countenance increased, and he seemed to be talking with someone. The fathers asked him of this; in his humility, he said he was asking the Angels for time to repent. The fathers told him, 'You have no need of repentance, Abba.' Abba Sisoes responded, 'I tell you the truth, I have not even made a beginning of it.' Thus they learned he was perfect. Again his face became as bright as the sun, so that the fathers were filled with fear. He said, 'Behold, the Lord is come, and He says, "Bring Me the vessel of the desert,"' and as he gave up his soul into the hands of God, there was as it were a flash of lightning, and the whole dwelling was filled with a sweet fragrance."

Concerning the icon of St. Sisoes staring over the dead bones of Alexander the Great, we do not know for sure if this depicts a historical event. We do not have a historical account of what the icon describes until its depiction first starts appearing in monasteries in Greece following the Fall of Constantinople in 1453.
The inscription on the icon reads:
Sisoes, the great ascetic, before the tomb of Alexander, King of the Greeks, who was once covered in glory. Astonished, he mourns for the vicissitudes of time and the transience of glory, and tearfully declaims thus:
'The mere sight of you, tomb, dismays me and causes my heart to shed tears, as I contemplate the debt we, all men, owe. How can I possibly stand it? Oh, death! Who can evade you?'
The astonishment of Sisoes has been an icon of contemplation for all Christians, especially for monastics, since the 15th century and has spread so much in popularity that it appears throughout hundreds of Greek churches and monasteries. Among the most famous come from Holy Trinity Monastery and Varlaam Monastery at Meteora, and Hosios Loukas. The place in the church where this icon usually appears is on the opposite side of the altar area as people exit the church, where also the Dormition icon of the Theotokos also appears. It is wisely placed here so Christians can contemplate death as they leave the church.
It is no coincidence that this icon became so popular after the Fall of Constantinople. Constantinople, once the seat of the Roman Emperor from the time of Constantine the Great, always looked to Alexander as one of the most exemplary of rulers. In fact, this was a tradition of all the Roman Emperors. The historian Dion Cassius (155-235 AD) reports that after Augustus had visited the body of Alexander in Alexandria, he was asked if he also wanted to visit the tombs of the Ptolemies, the sovereigns of Hellenistic Egypt. He refused, saying: "I came to see a king and not dead men". Roman universal rule was considered an inheritance of the Roman Emperors received through Alexander.

Andrew Michael Chugg writes in his book The Quest for the Tomb of Alexander the Great:
"It was the most renowned and respected shrine in the Roman Empire, the object of veneration by Julius Caesar, Cleopatra, Octavian, Caligula, Hadrian, Severus, Caracalla and a host of other luminaries. It stood for centuries within a sacred precinct the size of a large town at the heart of the greatest Greek city in the world. Yet at the end of the 4th century AD, when the Christian emperor Theodosius outlawed paganism, it disappeared without trace, creating the greatest archaeological enigma of the ancient world. What became of the tomb of Alexander the Great? Does any part of it still survive?"
"Ammianus Marcellinus relates an incident which took place in about AD 361. The Patriarch (Christian Archbishop) Georgius is said to have posed a rhetorical question to the Alexandrian mob concerning a tall and splendid temple of the Genius of Alexandria: 'How long shall this tomb stand?' he enquired. By 'Genius' Ammianus meant the tutelary deity of the city and this could well mean Alexander. Certainly, Alexander is the only figure to whom this expression might apply whose tomb also lay within the city. A few years later in AD 365, Alexandria was struck by a phenomenal earthquake followed by a gigantic tsunami, which is reported to have wrought havoc in coastal regions and port cities throughout the eastern Mediterranean. Alexandria is reported to have been particularly hard hit with ships being lifted onto the roofs of surviving buildings. This is the most probable occasion of the destruction of the Soma Mausoleum.
A quarter of a century later, in a newly recognised reference, Libanius of Antioch mentioned in an oration addressed to the emperor Theodosius that Alexander's corpse was on display in Alexandria. This would fit with the tomb chamber having eventually been excavated from beneath the rubble of the ruins. It also provides an occasion upon which the corpse might have been removed and separated from the sarcophagus, which would explain why the latter was found in a vacant state by Napoleon's expedition. A year or so later, Theodosius issued a series of decrees outlawing the worship of pagan gods, among whom Alexander was to the fore. In Alexandria, the Christians rioted and destroyed the Serapeum, the leading pagan temple. This is the point where the continued worship of the founder's corpse would have become unconscionable to the Alexandrian authorities. This is the time that Alexander's remains finally disappear from history. At the very end of the 4th century or early in the 5th, John Chrysostom was able to assert in a sermon that Alexander's tomb was then 'unknown to his own people', that is to say, to the pagans of Alexandria. A few decades later Theodoret listed Alexander among famous men whose tombs were unknown."
In light of this information, it is not implausible that the depiction of Sisoes lamenting over the tomb of Alexander is a historical event lost to us in document form but survives only in iconography. In many ways, the iconographic tradition is just as reliable historically as is a written document. Since Sisoes was a contemporary of the events described above regarding the destruction of Alexander's tomb, I would find it difficult to believe that such a wise disciple of Anthony the Great living outside Alexandria would not at least make some comment in this regard.
Sisoes lamenting over Alexander is also a lament over an ideology. It is not by coincidence that both men are known by the epithet "Great". At one time, during Roman rule that lasted over a millennium and a half, Alexander was an icon of the Empire, but now that the Empire was gone the Romans looked to monastics as the only hope for suffering Orthodoxy under the Ottoman Muslims. It is this outlook which formed the Orthodox mentality during this period. That is not to say that it did not exist before, since this was always a part of christian and monastic tradition, but now Sisoes stands over Alexander's dead bones alive and learning the great lesson of the vanity of worldly glory. Roman glory may have vanished, but the Kingdom of Heaven reigns forever.
